A report from the National Center for Health Statistics indicates the 2015 Alabama death rate from drug overdoses was at the national average, while MS and Georgia had a rate lower than the national average.
The highest rates of drug overdose deaths occurred in West Virginia, New Hampshire, Kentucky and Ohio.
Heroin caused more drug overdoses than any other drug.
Efforts to reduce overdose deaths should also focus on increasing access to evidenced-based treatments for substance use disorders, Mooney said.
Opioids killed more than 33,000 Americans in 2015, more than any year on record, the CDC said, which estimates that 91 Americans die every day from an opioid overdose.
The states with the highest age-adjusted intrastate rates of overdose deaths in 2015 were West Virginia (41.5 deaths per 100,000), New Hampshire (34.3), Kentucky (29.9), OH (29.9) and Rhode Island (28.2), while 16 other states also had death rates higher than the national rate of overdose deaths (16.3). In 1999, the percentage of drug overdoses related to heroin use was 8%, but the new 25% statistic more than triples its predecessor.
But the increase was not all due to opioids, the percent of drug deaths from cocaine increased to 13 percent in 2015 compared to 11 percent in 2010.
Deaths caused by heroin overdoses in the United States quadrupled between 2010 and 2015, according to a new report. But the rate grew the fastest - an average of 10.5 percent per year from 1999 to 2015 - among adults between 55 and 64 years old.
The National Center for Health Statistics said Friday the massive increase in heroin and general opioid abuse in the USA since 2010 is driven by lower drug prices and ever higher potency. In Wisconsin, policy makers launched an opioid task force and facilitated lower prices on an anti-overdose drug.
During the 16-year study period, the rate of overdose deaths among white people almost quadrupled, from 6 deaths per 100,000 people in 1999 to 21 deaths per 100,000 people in 2015.
Dr. Corey Slovis, chairman of department of emergency medicine at Vanderbilt University Medical Center and medical director of the National Fire Department and National Airport, said the current drug epidemic is "the worst that I've ever seen it", according to ABC.
The US Drug Enforcement Agency, tasked with monitoring and enforcing the country's federal laws on drugs, says heroin seizures increased.
The heroin and opioid epidemic has taken its toll.