It had four people on board - one crew member and three passengers, when it crashed. Officials said that the crash happened amid clear skies and a light wind.
Image: The plane had taken off from Tires aerodrome shortly before.
A plane has crashed into a supermarket near the Portuguese capital of Lisbon, killing five people and injuring several others.
The injured were shopping inside the supermarket, which is located in a residential neighborhood, and were treated for shock and smoke inhalation.
The Tires airfield said the plane was a twin-engine Piper PA-31 Navajo aircraft and was Swiss-registered.
One nearby house was also blackened by smoke.
The accident was attended by 50 rescue workers, and around 36 firefighting vehicles.
Tires is about 20km (12 miles) from Lisbon.The crash site is a auto park in a residential area between Lisbon and the upmarket resort of Cascais.Dozens of firefighters are at the scene.
"There are four dead, the pilot and his three passengers", a spokesman for Portugal's Office of Prevention and Investigation of Aeronautical Accidents told AFP, saying further details about the incident and the fatalities were not immediately known.
Authorities declined to identify those killed in the plane until their identities could be compared with the flight manifesto.